California Oncology
Research Institute
California Oncology
Research Institute
Research Projects
Completed and Ongoing Research Projects Funded by CORI
General Cancer Research
- Redefine staging systems in cancer to improve the selection of patients for different therapies.
- Evaluate the impact of age on adherence to quality measures in cancer care.
- Establish predictive statistical models to improve the selection of patients for chemotherapy.
- Study stem cells as biomarkers in cancer.
- Examine whether community hospitals are meeting the same standards as academic hospitals for the multimodal management of cancer.
- Examine the role of tumor infiltrating immune cells in tumor invasion and metastases.
- Establish evidence-based guidelines for precision risk stratification in cancer.
Liver Cancer
- Describe the benefits and risks of novel anti-angiogenesis therapies after liver resection.
- Develop novel, minimally invasive ways to destroy liver tumors.
- Examine the effects of long-acting somatostatin analogues plus aggressive cytoreductive surgery in patients with metastatic neuroendocrine carcinoma.
Colon Cancer
- Perform international multicenter trials to individualize cancer care in colon cancer.
- Develop new techniques for targeting lymph node assessment in gastrointestinal neoplasms.
- Describe a novel primary tumor gene signature in colon cancer when national quality standards are adhered to.
- Establish an immunoprofile for the prognostic assessment of colon cancer.
- Study sex-specific differences in colon cancer.
Breast Cancer
- Conduct a double-blind randomized controlled trial in breast cancer by adding 1% lidocaine to technetium sulfur colloid for sentinel lymphatic mapping.
Melanoma
- Conduct an extensive 45-year review in anorectal malignant melanoma and propose a novel staging classification.
- Evaluate whether there is an expanding role for hepatic resection and adrenalectomy in metastatic melanoma.
Stomach
- Evaluate whether surgical quality improves staging accuracy in gastric cancer.
- Determine whether race influences stage-specific survival in gastric cancer.
- Examine the impact of birthplace in Asian-Americans with gastric cancer.
Gallbladder
- Perform a prospective randomized controlled trial comparing standard analgesia with combined intra-operative cystic plate and port-site local anesthesia for post-operative pain management in patients undergoing a laparoscopic cholecystectomy.
Cancer education and training
- Evaluate attitudes and perceptions of surgical oncology fellows on ACGME accreditation and the complex general surgical oncology certification.
